Publications in which Jean Gotman is an author



Mooij AH, Frauscher B, Amiri M, Otte WM, Gotman J. Differentiating epileptic from non-epileptic high frequency intracerebral EEG signals with measures of wavelet entropy. Clin Neurophysiol. 2016 Dec;127(12):3529-3536.


Maneshi M, Vahdat S, Gotman J, Grova C. Validation of Shared and Specific Independent Component Analysis (SSICA) for Between-Group Comparisons in fMRI. Front Neurosci. 2016 Sep 27;10:417.


Jayakar P, Gotman J, Harvey AS, Palmini A, Tassi L, Schomer D, Dubeau F,Bartolomei F, Yu A, Kršek P, Velis D, Kahane P. Diagnostic utility of invasive EEG for epilepsy surgery: Indications, modalities, and techniques. Epilepsia.2016 Nov;57(11):1735-1747.


Ferrari-Marinho T, Perucca P, Dubeau F, Gotman J. Intracranial EEG seizure onset-patterns correlate with high-frequency oscillations in patients with drug-resistant epilepsy. Epilepsy Res. 2016 Sep 6;127:200-206.


Gotman J. Gamma oscillations or spikes? Epilepsia. 2016 Sep;57(9):1523-4.


Amiri M, Frauscher B, Gotman J. Phase-Amplitude Coupling Is Elevated in Deep Sleep and in the Onset Zone of Focal Epileptic Seizures. Front Hum Neurosci. 2016 Aug 3;10:387.


Jacobs J, Banks S, Zelmann R, Zijlmans M, Jones-Gotman M, Gotman J. Spontaneous ripples in the hippocampus correlate with epileptogenicity and not memory function in patients with refractory epilepsy. Epilepsy Behav. 2016, Sep;62:258-66.


Hao Y, Khoo HM, von Ellenrieder N, Gotman J. Subject-level reliability analysis of fast fMRI with application to epilepsy. Magn Reson Med. 2016 Aug 4. [Epub ahead of print]


von Ellenrieder N, Frauscher B, Dubeau F, Gotman J. Interaction with slow waves during sleep improves discrimination of physiologic and pathologic high-frequency oscillations (80-500 Hz). Epilepsia. 2016 Jun;57(6):869-78


von Ellenrieder N, Dan J, Frauscher B, Gotman J. Sparse asynchronous cortical generators can produce measurable scalp EEG signals. Neuroimage. 2016 Sep;138:123-33.


Frauscher B, von Ellenrieder N, Dubeau F, Gotman J. EEG desynchronization during phasic REM sleep suppresses interictal epileptic activity in humans. Epilepsia. 2016 Apr 25.


Avoli M, De Curtis M, Gnatkovsky V, Gotman J, Köhling R, Lévesque M, Manseau F, Shiri Z, Williams S. Specific imbalance of excitatory/inhibitory signaling establishes seizure onset pattern in temporal lobe epilepsy. J Neurophysiol. 2016 Apr 13:jn.01128.2015.


Lee K, Lina JM, Gotman J, Grova C. SPARK: Sparsity-based analysis of reliable k-hubness and overlapping network structure in brain functional connectivity. Neuroimage. 2016 Apr 2;134:434-449.


Asano E, Gotman J. Is electrocorticography-based language mapping ready to replace stimulation? Neurology. 2016 Mar 29;86(13):1174-6.


Pizzo F, Frauscher B, Ferrari-Marinho T, Amiri M, Dubeau F, Gotman J. Detectability of Fast Ripples (>250 Hz) on the Scalp EEG: A Proof-of-Principle Study with Subdermal Electrodes. Brain Topogr. 2016 May;29(3):358-67.


Burnos S, Frauscher B, Zelmann R, Haegelen C, Sarnthein J, Gotman J. The morphology of high frequency oscillations (HFO) does not improve delineating the epileptogenic zone. Clin Neurophysiol. 2016 Apr;127(4):2140-8.


von Ellenrieder N, Pellegrino G, Hedrich T, Gotman J, Lina JM, Grova C, Kobayashi E. Detection and Magnetic Source Imaging of Fast Oscillations (40-160 Hz) Recorded with Magnetoencephalography in Focal Epilepsy Patients. Brain Topogr. 2016 Mar;29(2):218-31.

Pizzo F, Ferrari-Marinho T, Amiri M, Frauscher B, Dubeau F, Gotman J. When spikes are symmetric, ripples are not: Bilateral spike and wave above 80Hz in focal and generalized epilepsy. Clin Neurophysiol. 2016 Mar;127(3):1794-802


Guerrini R, Duchowny M, Jayakar P, Krsek P, Kahane P, Tassi L, Melani F, Polster T, Andre VM, Cepeda C, Krueger DA, Cross JH, Spreafico R, Cosottini M, Gotman J, Chassoux F, Ryvlin P, Bartolomei F, Bernasconi A, Stefan H, Miller I,Devaux B, Najm I, Giordano F, Vonck K, Barba C, Blumcke I. Diagnostic methods and treatment options for focal cortical dysplasia. Epilepsia. 2015 Nov;56(11):1669-86.


Korczyn AD, Schachter SC, Amlerova J, Bialer M, van Emde Boas W, Brázdil M, Brodtkorb E, Engel J Jr, Gotman J, Komárek V, Leppik IE, Marusic P, Meletti S, Metternich B, Moulin CJ, Muhlert N, Mula M, Nakken KO, Picard F, Schulze-Bonhage A, Theodore W, Wolf P, Zeman A, Rektor I. Third International Congress on Epilepsy, Brain and Mind: Part 1. Epilepsy Behav. 2015 Sep;50:116-37.


Frauscher B, Bernasconi N, Caldairou B, von Ellenrieder N, Bernasconi A, Gotman J, Dubeau F. Interictal Hippocampal Spiking Influences the Occurrence of Hippocampal Sleep Spindles. Sleep. 2015 Dec 1;38(12):1927-33.


Amiri M, Lina JM, Pizzo F, Gotman J. High Frequency Oscillations and spikes: Separating real HFOs from false oscillations. Clin Neurophysiol. 2016 Jan;127(1):187-96.

Gadhoumi K, Lina JM, Mormann F, Gotman J. Seizure prediction for therapeutic devices: A review. J Neurosci Methods. 2015 Jun 19. pii: S0165-0270(15)00227-7.

Safi-Harb M, Proulx S, von Ellenrieder N, Gotman J. Advantages and disadvantages of a fast fMRI sequence in the context of EEG-fMRI investigation of epilepsy patients: A realistic simulation study. Neuroimage. 2015 Oct 1;119:20-32. doi: 10.1016

van Klink N, Frauscher B, Zijlmans M, Gotman J. Relationships between interictal epileptic spikes and ripples in surface EEG. Clin Neurophysiol. 2016 Jan;127(1):143-9.

Jacobs J, Vogt C, LeVan P, Zelmann R, Gotman J, Kobayashi K. The identification of distinct high-frequency oscillations during spikes delineates the seizure onset zone better than high-frequency spectral power changes. Clin Neurophysiol. 2016 Jan;127(1):129-42.

Menezes Cordeiro I, von Ellenrieder N, Zazubovits N, Dubeau F, Gotman J, Frauscher B. Sleep influences the intracerebral EEG pattern of focal cortical dysplasia. Epilepsy Res. 2015 Jul;113:132-9.

Gadhoumi K, Gotman J, Lina JM. Scale invariance properties of intracerebral EEG improve seizure prediction in mesial temporal lobe epilepsy. PLoS One. 2015 Apr 13;10(4)

Frauscher B, von Ellenrieder N, Ferrari-Marinho T, Avoli M, Dubeau F, Gotman J. Facilitation of epileptic activity during sleep is mediated by high amplitude slow waves. Brain. 2015 Jun;138(Pt 6):1629-41.

Ferrari-Marinho T, Perucca P, Mok K, Olivier A, Hall J, Dubeau F, Gotman J. Pathologic substrates of focal epilepsy influence the generation of high-frequency oscillations. Epilepsia. 2015 Apr;56(4):592-8.

Salami P, Lévesque M, Gotman J, Avoli M. Distinct EEG seizure patterns reflect different seizure generation mechanisms. J Neurophysiol. 2015 Apr 1;113(7):2840-4.

An D, Dubeau F, Gotman J. BOLD responses related to focal spikes and widespread bilateral synchronous discharges generated in the frontal lobe. Epilepsia. 2015 Mar;56(3):366-74.

Dansereau CL, Bellec P, Lee K, Pittau F, Gotman J, Grova C. Detection of abnormal resting-state networks in individual patients suffering from focal epilepsy: an initial step toward individual connectivity assessment. Front Neurosci. 2014 Dec 23;8:419.

Frauscher B, von Ellenrieder N, Dubeau F, Gotman J. Scalp spindles are associated with widespread intracranial activity with unexpectedly low synchrony. Neuroimage. 2015 Jan 15;105:1-12.

Kobayashi K, Akiyama T, Ohmori I, Yoshinaga H, Gotman J. Action potentials contribute to epileptic high-frequency oscillations recorded with electrodes remote from neurons. Clin Neurophysiol. 2015 May;126(5):873-81.

Fahoum F, Melani F, Andrade-Valença L, Dubeau F, Gotman J. Epileptic scalp ripples are associated with corticothalamic BOLD changes. Epilepsia. 2014 Oct;55(10):1611-9.

von Ellenrieder N, Beltrachini L, Muravchik CH, Gotman J. Extent of cortical generators visible on the scalp: effect of a subdural grid. Neuroimage. 2014 Nov 1;101:787-95.

Maneshi M, Vahdat S, Fahoum F, Grova C, Gotman J. Specific resting-state brain networks in mesial temporal lobe epilepsy. Front Neurol. 2014 Jul 14;5:127.

Luo C, An D, Yao D, Gotman J. Patient-specific connectivity pattern of epileptic network in frontal lobe epilepsy. Neuroimage Clin. 2014 Apr 16;4:668-75.

Watanabe S, An D, Safi-Harb M, Dubeau F, Gotman J. Hemodynamic response function (HRF) in epilepsy patients with hippocampal sclerosis and focal cortical dysplasia. Brain Topogr. 2014 Sep;27(5):613-9.

Salami P, Lévesque M, Benini R, Behr C, Gotman J, Avoli M. Dynamics of interictal spikes and high-frequency oscillations during epileptogenesis in temporal lobe epilepsy. Neurobiol Dis. 2014 Jul;67:97-106.

von Ellenrieder N, Beltrachini L, Perucca P, Gotman J. Size of cortical generators of epileptic interictal events and visibility on scalp EEG. Neuroimage. 2014 Jul 1;94:47-54.

Heers M, Hedrich T, An D, Dubeau F, Gotman J, Grova C, Kobayashi E. Spatial correlation of hemodynamic changes related to interictal epileptic discharges with electric and magnetic source imaging. Hum Brain Mapp. 2014

Proulx S, Safi-Harb M, Levan P, An D, Watanabe S, Gotman J. Increased sensitivity of fast BOLD fMRI with a subject-specific hemodynamic response function and application to epilepsy. Neuroimage. 2014 Jun;93 Pt 1:59-73.

Verdonck O, Reed SJ, Hall J, Gotman J, Plourde G. The sensory thalamus and cerebral motor cortex are affected concurrently during induction of anesthesia with propofol: a case series with intracranial electroencephalogram recordings.
Can J Anaesth. 2014 Mar;61(3):254-62.

Zelmann R, Lina JM, Schulze-Bonhage A, Gotman J, Jacobs J. Scalp EEG is not a blur: it can see high frequency oscillations although their generators are small. Brain Topogr. 2014 Sep;27(5):683-704.

Verdonck O, Reed SJ, Hall J, Gotman J, Plourde G. The sensory thalamus and cerebral motor cortex are affected concurrently during induction of anesthesia with propofol: a case series with intracranial electroencephalogram recordings.Can J Anaesth. 2014 Mar;61(3):254-262.


Xue K, Luo C, Zhang D, Yang T, Li J, Gong D, Chen L, Medina YI, Gotman J, Zhou D, Yao D. Diffusion tensor tractography reveals disrupted structural connectivity in childhood absence epilepsy. Epilepsy Res. 2014 Jan;108(1):125-38


Perucca P, Dubeau F, Gotman J. Widespread EEG changes precede focal seizures. PLoS One. 2013 Nov 19;8(11):e80972


An D, Fahoum F, Hall J, Olivier A, Gotman J, Dubeau F.Electroencephalography/functional magnetic resonance imaging responses help predict surgical outcome in focal epilepsy. Epilepsia. 2013 Dec;54(12):2184-94. Perucca P, Dubeau F, Gotman J. Intracranial electroencephalographic seizure-onset patterns: effect of underlying pathology. Brain. 2014 Jan;137(Pt 1):183-96.


Raux M, Tyvaert L, Ferreira M, Kindler F, Bardinet E, Karachi C,Morelot-Panzini C, Gotman J, Pike GB, Koski L, Similowski T. Functional magnetic resonance imaging suggests automatization of the cortical response to inspiratory threshold loading in humans. Respir Physiol Neurobiol. 2013 Dec 1;189(3):571-80

Melani F, Zelmann R, Dubeau F, Gotman J. Occurrence of scalp-fast oscillations among patients with different spiking rate and their role as epileptogenicity marker. Epilepsy Res. 2013 Oct;106(3):345-356

Fahoum F, Zelmann R, Tyvaert L, Dubeau F, Gotman J. Epileptic discharges affect the default mode network--FMRI and intracerebral EEG evidence. PLoS One. 2013 Jun 28;8(6):e68038

van Diessen E, Hanemaaijer JI, Otte WM, Zelmann R, Jacobs J, Jansen FE, Dubeau F, Stam CJ, Gotman J, Zijlmans M. Are high frequency oscillations associated with altered network topology in partial epilepsy? Neuroimage. 2013 Nov 15;82:564-73

Pittau F, Fahoum F, Zelmann R, Dubeau F, Gotman J. Negative BOLD Response to Interictal Epileptic Discharges in Focal Epilepsy. Brain Topogr. 2013 Oct;26(4):627-40

Melani F, Zelmann R, Mari F, Gotman J. Continuous High Frequency Activity: a peculiar SEEG pattern related to specific brain regions. Clin Neurophysiol. 2013 Aug;124(8):1507-16.

Châtillon CE, Zelmann R, Hall JA, Olivier A, Dubeau F, Gotman J. Influence of contact size on the detection of HFOs in human intracerebral EEG recordings. Clin Neurophysiol. 2013 Aug;124(8)


Kucewicz MT, Worrell GA, Gotman J. Pathologic brain network activity: Memory impairment in epilepsy. Neurology. 2013 Jul 2;81(1):12-3


Gadhoumi K, Lina JM, Gotman J. Seizure prediction in patients with mesial temporal lobe epilepsy using EEG measures of state similarity. Clin Neurophysiol. 2013 Sep;124(9):1745-54


Kay BP, Difrancesco MW, Privitera MD, Gotman J, Holland SK, Szaflarski JP. Reduced default mode network connectivity in treatment-resistant idiopathic generalized epilepsy. Epilepsia. 2013 Mar;54(3):461-70


 Haegelen C, Perucca P, Châtillon CE, Andrade-Valença L, Zelmann R, Jacobs J, Collins DL, Dubeau F, Olivier A, Gotman J. High-frequency oscillations, extent of surgical resection, and surgical outcome in drug-resistant focal epilepsy. Epilepsia. 2013 May;54(5):848-57


 Szaflarski JP, Kay B, Gotman J, Privitera MD, Holland SK. The relationship between the localization of the generalized spike and wave discharge generators and the response to valproate. Epilepsia. 2013 Mar;54(3):471-80


 Maneshi M, Moeller F, Fahoum F, Gotman J, Grova C. Resting-state connectivity of the sustained attention network correlates with disease duration in idiopathic generalized epilepsy. PLoS One. 2012;7(12):e50359.

 .     Fahoum F, Lopes R, Pittau F, Dubeau F, Gotman J Widespread epileptic networks in focal epilepsies-EEG-fMRI study. Epilepsia. 2012 Sep;53(9):1618-27

       Vahdat S, Maneshi M, Grova C, Gotman J, Milner TE. Shared and Specific Independent Components Analysis for Between-Group Comparison. Neural Comput. 2012 Nov;24(11):3052-90

 Salami P, Lévesque M, Gotman J, Avoli M. A comparison between automated detection methods of high-frequency oscillations (80-500Hz) during seizures. J Neurosci Methods. 2012 Nov 15;211(2):265-71

 Lévesque M, Salami P, Gotman J, Avoli M. Two seizure-onset types reveal specific patterns of high-frequency oscillations in a model of temporal lobe epilepsy. J Neurosci. 2012 Sep 19;32(38):13264-72.

      Jackson GD, Badawy R, Gotman J. Functional magnetic resonance imaging: focus localization. Handb Clin Neurol. 2012;107:369-85.

       Finke S, Gulrajani RM, Gotman J, Savard P Conventional and Reciprocal Approaches to the Inverse Dipole Localization Problem for N(20)-P (20) Somatosensory Evoked Potentials. Brain Topogr. 2012 Jun 22. [Epub ahead of print]  

       Ayoubian L, Lacoma H, Gotman J Automatic seizure detection in SEEG using high frequency activities in wavelet domain. Med Eng Phys. 2012 May 29. [Epub ahead of print]


        Pittau F, Grova C, Moeller F, Dubeau F, Gotman J Patterns of altered functional connectivity in mesial temporal lobe epilepsy. Epilepsia. 2012 Jun;53(6):1013-23.


        Pittau F, Dubeau F, Gotman J Contribution of EEG/fMRI to the definition of the epileptic focus. Neurology. 2012 May 8;78(19):1479-87


       Jacobs J, Staba R, Asano E, Otsubo H, Wu JY, Zijlmans M, Mohamed I, Kahane P, Dubeau F, Navarro V, Gotman J High-frequency oscillations (HFOs) in clinical epilepsy. Prog Neurobiol. 2012 Apr 3. [Epub ahead of print]


       Gadhoumi K, Lina JM, Gotman J Discriminating preictal and interictal states in patients with temporal lobe epilepsy using wavelet analysis of intracerebral EEG. Clin Neurophysiol. 2012 Oct;123(10)


       Mari F, Zelmann R, Andrade-Valenca L, Dubeau F, Gotman J Continuous high-frequency activity in mesial temporal lobe structures. Epilepsia. 2012 May;53(5):797-806


       Zijlmans M, Jiruska P, Zelmann R, Leijten FS, Jefferys JG, Gotman J High-frequency oscillations as a new biomarker in epilepsy. Ann Neurol. 2012 Feb;71(2):169-78


       Lopes R, Lina JM, Fahoum F, Gotman J Detection of epileptic activity in fMRI without recording the EEG. Neuroimage. 2012 Apr 15;60(3):1867-79


       Goldenholz DM, Seyal M, Bateman LM, Gotman J, Andrade-Valenca L, Zelmann R, Dubeau F Interictal scalp fast oscillations as a marker of the seizure onset zone. Neurology. 2012 Jan 17;78(3):224-5


       Gotman J A few thoughts on "What is a seizure?". Epilepsy Behav. 2011 Dec;22 Suppl 1:S2-3.


       Worrell G, Gotman J. High-frequency oscillations and other electrophysiological biomarkers of epilepsy: clinical studies. Biomark Med. 5:557-66, 2011. 


    Andrade-Valença L, Mari F, Jacobs J, Zijlmans M, Olivier A, Gotman J, Dubeau F. Interictal high frequency oscillations (HFOs) in patients with focal epilepsy and normal MRI. Clin Neurophysiol. 2012 Jan;123(1):100-5


    Andrade-Valenca LP, Dubeau F, Mari F, Zelmann R, Gotman J. Interictal scalp fast oscillations as a marker of the seizure onset zone. Neurology 77(6):524-31, 2011. 


    von Ellenrieder N, Andrade-Valença LP, Dubeau F, Gotman J. Automatic detection of fast oscillations (40-200Hz) in scalp EEG recordings. Clin Neurophysiol. 2012 Apr;123(4):670-80


    Gotman J, Pittau F. Combining EEG and fMRI in the study of epileptic discharges. Epilepsia  4:38-42, 2011. 


    Zelmann R, Mari F, Jacobs J, Zijlmans M, Dubeau F, Gotman J. A comparison between detectors of high frequency oscillations. Clin Neurophysiol. 2012 Jan;123(1):106-16


    Moeller F, Maneshi M, Pittau F, Gholipour T,  Bellec P, Dubeau F, Grova C, Gotman J. Functional connectivity in patients with idiopathic generalized epilepsy. Epilepsia 52(3):515-22, 2011.


    Levesque M, Bortel A, Gotman J, Avoli M.  High frequency (80-500 Hz) oscillations and epiletogenesis in temporal lobe epilepsy. Neurobiology of Disease 42(3):231-41, 2011. 


    Khatamian YB, Fahoum F, Gotman J. Limits of 2D-TCA in detecting BOLD responses to epileptic activity. Epilepsy Res 2011 [Epub ahead of print] 


    Gu H, Gotman J, Webb JP. Computed basis functions for finite element analysis based on tomographic data. IEEE Trans Biomed Eng 58(9):2498-505, 2011. 


    Pittau F, Levan P, Moeller F, Gholipour T, Haegelen C, Zelmann R, Dubeau F, Gotman J. Changes preceding interictal epileptic EEG abnormalities: comparison between EEG/fMRI and intracerebral EEG. Epilepsia 52(6):1120-9, 2011.


   Gholipour T, Moeller F, Pittau F, Dubeau F, Gotman J. Reproducibility of interictal EEG-fMRI results in patients with epilepsy. Epilepsia 52(3):433-42, 2011.


   Zijlmans M, Jacobs J, Kahn YU, Zelmann R, Dubeau F, Gotman J. Ictal and interictal high frequency oscillations in patients with focal epilepsy. Clin Neurophysiol 122(4):664-71, 2011.


   Châtillon CÉ, Zelmann R, Bortel A, Avoli M, Gotman J. Contact size does not affect high frequency oscillation detection in intracerebral EEG recordings in a rat epilepsy model. Clin Neurophysiol 122(9):1701-5, 2011.

Rathakrishnan R, Gotman J, Dubeau F, Angle M. Using continuous electroencephalography in the management of delayed cerebral ischemia following subarachnoid hemorrhage. Neurocrit Care. 2011 Apr;14(2):152-61.

Zelmann R, Mari F, Jacobs J, Zijlmans M, Chander R, Gotman J. Automatic detector of high frequency oscillations for human recordings with macroelectrodes. Conf Proc IEEE Eng Med Biol Soc. 2010:2329-33.

Zijlmans M, Jacobs J, Kahn YU, Zelmann R, Dubeau F, Gotman J. Ictal and interictal high frequency oscillations in patients with focal epilepsy. Clin Neurophysiol. 2011 Apr;122(4):664-71

Navarro V, Le Van Quyen M, Clemenceau S, Adam C, Petitmengin C, Dubeau F, Gotman J, Martinerie J, Baulac M. Seizure prediction: from myth to reality. Rev Neurol (Paris). 2011 Mar;167(3):205-15.

Moeller F, LeVan P, Muhle H, Stephani U, Dubeau F, Siniatchkin M, Gotman J. Absence seizures: individual patterns revealed by EEG-fMRI. Epilepsia. 2010 Oct;51(10):2000-10.

Frei MG, Zaveri HP, Arthurs S, Bergey GK, Jouny CC, Lehnertz K, Gotman J, Osorio I, Netoff TI, Freeman WJ, Jefferys J, Worrell G, Quyen Mle V, Schiff SJ, Mormann F. Controversies in epilepsy: debates held during the Fourth International Workshop on Seizure Prediction. Epilepsy Behav. 2010 Sep;19(1):4-16.

Bortel A, Lévesque M, Biagini G, Gotman J, Avoli M. Convulsive status epilepticus duration as determinant for epileptogenesis and interictal discharge generation in the rat limbic system. Neurobiol Dis. 2010 Nov;40(2):478-89.

Jacobs J, Kobayashi K, Gotman J. High-frequency changes during interictal spikes detected by time-frequency analysis. Clin Neurophysiol. 2011 Jan;122(1):32-42

Szaflarski JP, DiFrancesco M, Hirschauer T, Banks C, Privitera MD, Gotman J, Holland SK. Cortical and subcortical contributions to absence seizure onset examined with EEG/fMRI. Epilepsy Behav. 2010 Aug;18(4):404-13.

Rathakrishnan R, Moeller F, Levan P, Dubeau F, Gotman J. BOLD signal changes preceding negative responses in EEG-fMRI in patients with focal epilepsy. Epilepsia. 2010 Sep;51(9):1837-45.

Gotman J. High frequency oscillations: the new EEG frontier? Epilepsia. 2010 Feb;51 Suppl 1:63-5.

Gotman J, Dubeau F. Introduction: Epilepsy at the cutting edge: a meeting in honor of Fred and Eva Andermann. Epilepsia. 2010 Feb;51 Suppl 1:1-2.

Moeller F, Levan P, Gotman J. Independent component analysis (ICA) of generalized spike wave discharges in fMRI: Comparison with general linear model-based EEG-fMRI. Hum Brain Mapp. 2011 Feb;32(2):209-17

Jacobs J, Zijlmans M, Zelmann R, Chatillon CE, Hall J, Olivier A, Dubeau F, Gotman J. High-frequency electroencephalographic oscillations correlate with outcome of epilepsy surgery. Ann Neurol. 2010 Feb;67(2):209-20.

Schelter B, Feldwisch-Drentrup H, Timmer J, Gotman J, Schulze-Bonhage A. A common strategy and database to compare the performance of seizure prediction algorithms. Epilepsy Behav. 2010 Feb;17(2):154-156. Epub 2009 Dec 30.


Levan P, Tyvaert L, Gotman J. Modulation by EEG features of BOLD responses to interictal epileptiform discharges. Neuroimage. 2010 Mar;50(1):15-26. Epub 2009 Dec 21.


Moeller F, Tyvaert L, Nguyen DK, LeVan P, Bouthillier A, Kobayashi E, Tampieri D, Dubeau F, Gotman J. EEG-fMRI: adding to standard evaluations of patients with nonlesional frontal lobe epilepsy. Neurology. 2009 Dec 8;73(23):2023-30.


Tyvaert L, Chassagnon S, Sadikot A, LeVan P, Dubeau F, Gotman J. Thalamic nuclei activity in idiopathic generalized epilepsy: an EEG-fMRI study. Neurology. 2009 Dec 8;73(23):2018-22.


Kobayashi K, Agari T, Oka M, Yoshinaga H, Date I, Ohtsuka Y, Gotman J. Detection of seizure-associated high-frequency oscillations above 500Hz. Epilepsy Res. 2010 Feb;88(2-3):139-44. Epub 2009 Nov 14.


Jacobs J, Zijlmans M, Zelmann R, Olivier A, Hall J, Gotman J, Dubeau F. Value of electrical stimulation and high frequency oscillations (80-500 Hz) in identifying epileptogenic areas during intracranial EEG recordings. Epilepsia. 2010 Apr;51(4):573-82. Epub 2009 Oct 20.

D'Antuono M, Köhling R, Ricalzone S, Gotman J, Biagini G, Avoli M. Antiepileptic drugs abolish ictal but not interictal epileptiform discharges in vitro. Epilepsia. 2010 Mar;51(3):423-31. Epub 2009 Aug 19.

Levan P, Tyvaert L, Moeller F, Gotman J. Independent component analysis reveals dynamic ictal BOLD responses in EEG-fMRI data from focal epilepsy patients. Neuroimage. 2010 Jan 1;49(1):366-78. Epub 2009 Aug 6.

Moeller F, Siebner HR, Ahlgrimm N, Wolff S, Muhle H, Granert O, Boor R, Jansen O, Gotman J, Stephani U, Siniatchkin M. fMRI activation during spike and wave discharges evoked by photic stimulation. Neuroimage. 2009 Dec;48(4):682-95. Epub 2009 Jul 18.

Zelmann R, Zijlmans M, Jacobs J, Châtillon CE, Gotman J. Improving the identification of High Frequency Oscillations. Clin Neurophysiol. 2009 Aug;120(8):1457-64. Epub 2009 Jul 2.

Kobayashi E, Grova C, Tyvaert L, Dubeau F, Gotman J. Structures involved at the time of temporal lobe spikes revealed by interindividual group analysis of EEG/fMRI data. Epilepsia. 2009 Dec;50(12):2549-56. Epub 2009 Jun 22.

Tyvaert L, Levan P, Dubeau F, Gotman J. Noninvasive dynamic imaging of seizures in epileptic patients. Hum Brain Mapp. 2009 Dec;30(12):3993-4011.

Chassagnon S, Hawko CS, Bernasconi A, Gotman J, Dubeau F. Coexistence of symptomatic focal and absence seizures: Video-EEG and EEG-fMRI evidence of overlapping but independent epileptogenic networks. Epilepsia. 2009 Jul;50(7):1821-6. Epub 2009 Apr 27.

 Zijlmans M, Jacobs J, Zelmann R, Dubeau F, Gotman J. High frequency oscillations and seizure frequency in patients with focal epilepsy. Epilepsy Res. 2009 Aug;85(2-3):287-92.

Jacobs J, Zelmann R, Jirsch J, Chander R, Dubeau CE, Gotman J. High frequency oscillations (80-500 Hz) in the preictal period in patients with focal seizures. Epilepsia. 2009 Jul;50(7):1780-92. Epub 2009 Mar 27..

Kobayashi K, Jacobs J, Gotman J. Detection of changes of high-frequency activity by statistical time-frequency analysis in epileptic spikes. Clin Neurophysiol. 2009 Jun;120(6):1070-7. Epub 2009 Apr 25.

Yu JM, Tyvaert L, Levan P, Zelmann R, Dubeau F, Gotman J, Kobayashi E. EEG spectral changes underlying BOLD responses contralateral to spikes in patients with focal epilepsy. Epilepsia. 2009 Jul;50(7):1804-9. Epub 2009 Apr 6.

Jacobs J, Levan P, Moeller F, Boor R, Stephani U, Gotman J, Siniatchkin M. Hemodynamic changes preceding the interictal EEG spike in patients with focal epilepsy investigated using simultaneous EEG-fMRI. Neuroimage. 2009 May 1;45(4):1220-31.

Jacobs J, Levan P, Châtillon CE, Olivier A, Dubeau F, Gotman J. High frequency oscillations in intracranial EEGs mark epileptogenicity rather than lesion type. Brain. 2009 Apr;132(Pt 4):1022-37.

Zijlmans M, Jacobs J, Zelmann R, Dubeau F, Gotman J. High-frequency oscillations mirror disease activity in patients with epilepsy. Neurology. 2009 Mar 17;72(11):979-86.

Tyvaert L, Levan P, Grova C, Dubeau F, Gotman J. Effects of fluctuating physiological rhythms during prolonged EEG-fMRI studies. Clin Neurophysiol. 2008 Dec;119(12):2762-74.

Bagshaw AP, Jacobs J, Levan P, Dubeau F, Gotman J. Effect of sleep stage on interictal high-frequency oscillations recorded from depth macroelectrodes in patients with focal epilepsy. Epilepsia. 2009 Apr;50(4):617-28.


Levan P, Gotman J. Independent component analysis as a model-free approach for the detection of BOLD changes related to epileptic spikes: A simulation study. Hum Brain Mapp. 2009 Jul;30(7):2021-31.


Miller JW, Gotman J. The meaning of interictal spikes in temporal lobe epilepsy: should we count them? Neurology. 2008 Aug 5;71(6):392-3.


Gotman J. Epileptic networks studied with EEG-fMRI. Epilepsia. 2008;49 Suppl 3:42-51.


Jacobs J, Levan P, Chander R, Hall J, Dubeau F, Gotman J. Interictal high-frequency oscillations (80-500 Hz) are an indicator of seizure onset areas independent of spikes in the human epileptic brain. Epilepsia. 2008 May 9.


Jacobs J, Hawco C, Kobayashi E, Boor R, Levan P, Stephani U, Siniatchkin M, Gotman J. Variability of the hemodynamic response as a function of age and frequency of epileptic discharge in children with epilepsy. Neuroimage. 2008 Apr 1;40(2):601-14.


Jacobs J, Rohr A, Moeller F, Boor R, Kobayashi E, Levan Meng P, Stephani U, Gotman J, Siniatchkin M. Evaluation of epileptogenic networks in children with tuberous sclerosis complex using EEG-fMRI. Epilepsia. 2008 Jan 2; [Epub ahead of print]


Grova C, Daunizeau J, Kobayashi E, Bagshaw AP, Lina JM, Dubeau F, Gotman J. Concordance between distributed EEG source localization and simultaneous EEG-fMRI studies of epileptic spikes. NeuroImage, in press, 2007


Jacobs J, Kobayashi E, Boor R, Muhle H, Stephan W, Hawco C, Dubeau F, Jansen O, Stephani U, Gotman J, Siniatchkin M. Hemodynamic responses to interictal epileptiform discharges in children with symptomatic epilepsy. Epilepsia. 2007 Nov;48(11):2068-78


Urrestarazu E, Chander R, Dubeau F, Gotman J. Interictal high-frequency oscillations (100-500 Hz) in the intracerebral EEG of epileptic patients. Brain. 2007 Sep;130(Pt 9):2354-66.


Hawco CS, Bagshaw AP, Lu Y, Dubeau F, Gotman J.BOLD changes occur prior to epileptic spikes seen on scalp EEG. Neuroimage. 2007 May 1;35(4):1450-8.


Velis D, Plouin P, Gotman J, da Silva FL; ILAE DMC Subcommittee on Neurophysiology. Recommendations regarding the requirements and applications for long-term recordings in epilepsy. Epilepsia. 2007 Feb;48(2):379-84.

Kobayashi E, Bagshaw AP, Gotman J, Dubeau F. Metabolic correlates of epileptic spikes in cerebral cavernous angiomas. Epilepsy Res. 2007 Jan;73(1):98-103.


Lu Y, Grova C, Kobayashi E, Dubeau F, Gotman J. Using voxel-specific hemodynamic response function in EEG-fMRI data analysis: An estimation and detection model. Neuroimage. 2007 Jan 1;34(1):195-203.


Bagshaw AP, Torab L, Kobayashi E, Hawco C, Dubeau F, Pike GB, Gotman J. EEG-fMRI using z-shimming in patients with temporal lobe epilepsy. J Magn Reson Imaging. 2006 Nov;24(5):1025-32.

Lu Y, Bagshaw AP, Grova C, Kobayashi E, Dubeau F, Gotman J. Using voxel-specific hemodynamic response function in EEG-fMRI data analysis. Neuroimage. 2006 Aug 1;32(1):238-47. Epub 2006 Jun 13.

Grova C, Makni S, Flandin G, Ciuciu P, Gotman J, Poline JB. Anatomically informed interpolation of fMRI data on the cortical surface. Neuroimage. 2006 Jul 15;31(4):1475-86. Epub 2006 May 2.

Gotman J, Kobayashi E, Bagshaw AP, Benar CG, Dubeau F. Combining EEG and fMRI: a multimodal tool for epilepsy research. J Magn Reson Imaging. 2006 Jun;23(6):906-20.

Jirsch JD, Urrestarazu E, LeVan P, Olivier A, Dubeau F, Gotman J.  High-frequency oscillations during human focal seizures. Brain. 2006 Jun;129(Pt 6):1593-608. Epub 2006 Apr 21.

Kobayashi E, Hawco CS, Grova C, Dubeau F,
Gotman J. Widespread and intense BOLD changes during brief focal electrographic seizures. Neurology. 2006 Apr 11;66(7):1049-55.

Kobayashi E, Bagshaw AP, Benar CG, Aghakhani Y, Andermann F, Dubeau F,
Gotman J. Temporal and extratemporal BOLD responses to temporal lobe interictal spikes. Epilepsia. 2006 Feb;47(2):343-54.

Urrestarazu E, LeVan P, Gotman J. Independent component analysis identifies ictal bitemporal activity in intracranial recordings at the time of unilateral discharges. Clin Neurophysiol. 2006 Mar;117(3):549-61. Epub 2006 Feb 7.

 LeVan P, Urrestarazu E, Gotman J. A system for automatic artifact removal in ictal scalp EEG based on independent component analysis and Bayesian classification. Clin Neurophysiol. 2006 Apr;117(4):912-27. Epub 2006 Feb 2.

Benar CG, Grova C, Kobayashi E, Bagshaw AP, Aghakhani Y, Dubeau F, Gotman J. Simultaneous EEG-fMRI of epileptic spikes: Concordance with EEG source localization and intracranial EEG. NeuroImage, 2006 Jan 11; [Epub ahead of print]

Bagshaw AP Kobayashi E, Dubeau D, Pike GB, Gotman J. Correspondence between EEG-fMRI and EEG Dipole Localisation of Interictal Discharges in Focal Epilepsy. NeuroImage, 2005 Oct 31 Epub.

Aghakhani Y, Kobayashi E, Bagshaw AP, Hawco CS, Bénar CG, Dubeau F, Gotman J. Cortical and Thalamic fMRI Responses in Partial Epilepsy with Focal and Bilateral Synchronous Spikes, Clinical Neurophysiology 117:177-191, 2006.

Grova C, Daunizeau J, Lina JM, Bénar CG, Benali H, Gotman J. Evaluation of EEG localization methods using realistic simulations of interictal spikes. Neuroimage, 29:734-753, 2006.

Kobayashi E, Bagshaw AP, Grova C, Gotman J, Dubeau F. Grey Matter Heterotopia: what EEG-fMRI can teach us about epileptogenicity of neuronal migration disorders. Brain, 129: 366-367, 2006.

Gotman J, Grova C, Bagshaw AP, Kobayashi E, Aghakhani Y and Dubeau F. Generalized Epileptic Discharges: Thalamo-cortical Activation and Suspension of the Default State of the Brain. Proc Natl Acad Sci USA, 102:15236-15240, 2005.

Chang N, Gulrajani R, Gotman J. Dipole localization using simulated intracerebral EEG. Clinical Neurophysiology, 116:2707-2716, 2005.

Jones-Gotman M, Sziklas V, Djordjevic J, Dubeau F, Gotman J, Angle M, Tampieri D, Olivier A, Andermann F. Etomidate speech and memory test (eSAM): A new drug and improved intracarotid procedure. Neurology, 65:1723-1729, 2005.

Stefanovic, B, Warnking JM, Kobayashi E, Bagshaw AP, Hawco C, Dubeau F, Gotman J, Pike B. Hemodynamic and Metabolic Responses to Activation, Deactivation and Epileptic Discharges. NeuroImage, 28:205-215, 2005.

Grewal S, Gotman J. An automatic warning system for epileptic seizures recorded on intracerebral EEGs. Clin Neurophysiol, 116:2460-2472, 2005.

Agarwal R, Takeuchi T, Laroche S, Gotman J. Detection of Rapid-Eye Movements in Sleep Studies. IEEE Trans Biomed Eng, 52:1390-1396, 2005.

Kobayashi E, Bagshaw A, Jansen A, Andermann F, Andermann E, Gotman J, Dubeau F. Intrinsic epileptogenicity in polymicrogyric cortex suggested by EEG-fMRI BOLD responses. Neurology, 64:1263-1266, 2005.

Aghakhani Y, Kinay D, Gotman J, Soualmi L, Andermann F, Olivier A Dubeau F. The Role of periventricular nodular heterotopia in epileptogenesis. Brain 128:641-651, 2005.

Navarro V, Martinerie J, Le Van Quyen M, Baulac M, Dubeau F, Gotman J. Seizure anticipation: do mathematical measures correlate with video-EEG evaluation? Epilepsia 46:385-96, 2005.

Kobayashi K, Yoshinaga H, Ohtsuka Y, Gotman J. Dipole modeling of epileptic spikes can be accurate or misleading. Epilepsia 46:397-408, 2005.

Zhou W, Gotman J. Removing Eye Movement Artefacts from the EEG during the intracarotid amobarbital procedure. Epilepsia 46:409-414, 2005.

Bagshaw A, Hawco C, Bénar C-G, Kobayashi E, Aghakhani Y, Dubeau F, Pike GB, Gotman J. Analysis of the EEG-fMRI response to prolonged bursts of interictal epileptiform activity. Neuroimage 24:1099-1112, 2005.

Bénar CG, Gunn RN, Grova C, Champagne B, Gotman J. Statistical maps for EEG dipolar source localization. IEEE Trans Biomed Eng 52:401-413, 2005.

Saab M, Gotman J. A system to detect the onset of epileptic seizures in scalp EEG. Clin Neurophysiol 116:427-442, 2005.

Gotman J, Bénar CG, Dubeau F. Combining EEG and fMRI in Epilepsy: Methodological Challenges and Clinical Results. J Clin Neurophysiol 21:229-240, 2004.

Asano E, Muzik O, Shah A, Juhász C, Chugani DC, Kagawa K, Benedek K, Sood S, Gotman J, Chugani HT. Quantitative visualization of ictal subdural EEG changes in children with neocortical focal seizures. Clin Neurophysiol 115:2718-2727, 2004.

Agha Khani Y, Rosati A, Olivier A, Gotman J, Andermann F, Dubeau F. The predictive localizing value of tonic limb posturing in supplementary sensorimotor seizures. Neurology 62:2256-2261, 2004.

Agha Khani Y, Bagshaw AP, Bénar CG, Hawco, C, Andermann F, Dubeau F, Gotman J. fMRI activation during spike and wave discharges in idiopathic generalized epilepsy. Brain 127:1127-1144, 2004.

Bagshaw AP, Agha Khani A, Benar CG, Kobayashi E, Hawco C, Dubeau F, Pike B, Gotman J. EEG-fMRI of focal epileptic spikes: analysis with multiple haemodynamic functions and comparison with gadolinium-enhanced MR angiograms. Human Brain Mapping 22:179-192, 2004.

Kang JK, Bénar CG, Al-Asmi A, Agha Khani Y, Pike B, Dubeau F, Gotman J. Using patient-specific hemodynamic response functions in combined EEG-fMRI studies in epilepsy. NeuroImage 20:1162-1170, 2003.

Benar CG, Aghakhani Y, Wang Y, Izenberg A, Al-Asmi A, Dubeau F, Gotman J. Quality of EEG in simultaneous EEG-fMRI for epilepsy. Clin Neurophysiology 114:569-580, 2003.

Al-Asmi A, Bénar CG, Gross DW, Agha Khani Y, Andermann F, Pike B, Dubeau F, Gotman J. fMRI Activation in Continuous and Spike-triggered EEG-fMRI Studies of Epileptic Spikes. Epilepsia 44:1328-1339, 2003.

Rosati A, Aghakhani Y, Bernasconi A, Olivier A, Andermann F, Gotman J, Dubeau F. Intractable temporal lobe epilepsy with rare spikes is less severe than with frequent spikes. Neurology 60: 1290-1295, 2003.

Kobayashi K, Yoshinaga H, Oka M, Ohtsuka Y, Gotman J. A simulation study of the error in dipole source localization for EEG spikes with a realistic head model. Clin Neurophysiol 114: 1069-1078, 2003.

Finke S, Gulrajani RM, Gotman J. Conventional and Reciprocal Approaches to the Inverse Dipole Localization Problem of Electroencephalography. IEEE Trans Biomed Eng, 50: 657-666, 2003.

Khan YU, Gotman J. Wavelet based automatic seizure detection in intracerebral EEG. Clin Neurophysiol 114:898-908, 2003.

Flanagan D, Agarwal R, Wang YH, Gotman J. Improvement in the performance of automated spike detection using dipole source features for artifact rejection. Clin Neurophysiol 114:38-49, 2003.

Asano E, Muzik O, Shah A, Juhász C, Chugani DC, Sood S, Janisse J, Ergun EL, Ahn-Ewing J, Shen C, Gotman J, Chugani, HT. Quantitative interictal subdural EEG analyses in children with neocortical epilepsy. Epilepsia 44:425-434, 2003.

Benar CG, Gross DW, Wang Y, Petre V, Pike B, Dubeau F, Gotman J. The BOLD response to interictal epileptiform discharges. NeuroImage 17:1182-1192, 2002.

Zijlmans M, Flanagan D, Gotman J. Heart rate changes and ECG abnormalities during epileptic seizures: prevalence and definition of an objective clinical sign. Epilepsia 43:847-854, 2002.

Agarwal R, Gotman J. Digital tools in polysomnography. J Clin Neurophysiol 19:136-143, 2002.

Flanagan D, Agarwal R, Gotman J. Computer-aided spatial classification of epileptic spikes. J Clin Neurophysiol 19:125-135, 2002.

Kobayashi K, Akiyama T, Nakahori T, Yoshinaga H, Gotman J. Systematic source estimation of spikes by a combination of independent analysis and RAP-MUSIC. II: Preliminary clinical application. Clin Neurophysiol 113:725-734, 2002.

Kobayashi K, Akiyama T, Nakahori T, Yoshinaga H, Gotman J. Systematic source estimation of spikes by a combination of independent component analysis and RAP-MUSIC. I: Principles and simulation study. Clin Neurophysiol 113:713-724, 2002.

Benar CG, Gotman J. Modeling of post-surgical brain and skull defects in the EEG inverse problem with the boundary element method. Clin Neurophysiol 113:48-56, 2002.

Agarwal R, Gotman J. Computer -assisted sleep staging. IEEE Trans Biomed Eng 48:1412-1423, 2001.

Agarwal R, Gotman J. Long-term EEG compression for intensive-care settings. IEEE Eng Med Biol 20:23-29, 2001.

Wang Y, Gotman J. The influence of electrode location errors on EEG dipole source localization with a realistic head model. Clin Neurophysiol 112:1777-1780, 2001.

Serles W, Li LM, Antel SB, Cendes F, Gotman J, Olivier A, Andermann F, Dubeau F, Arnold, DL. Time course of postoperative recovery of N-Acetyl-Aspartate in temporal lobe epilepsy. Epilepsia 42:190-197, 2001.

Merlet I, Gotman J. Dipole modeling of scalp electroencephalogram epileptic discharges: correlation with intracerebral fields. Clin Neurophysiol 112:414-430, 2001.

Kobayashi K, Merlet I, Gotman J. Separation of spikes from background by independent component analysis with dipole modeling and comparison to intracranial recording. Clin Neurophysiol 112:405-413, 2001.

Gross DW, Dubeau F, Quesney F, Gotman J. EEG Telemetry with closely spaced electrodes in frontal lobe epilepsy. J Clin Neurophysiol 17:414-418, 2000.

Bernasconi A, Bernasconi N, Lassonde M, Toussaint PJ, Meyer E, Reutens DC, Gotman J, Andermann F, Villemure JG. Sensorimotor organization in patients with porencephalic cyst who have undergone hemispherectomy: a study with 15O-water PET and somatosensory evoked potentials. NeuroReport 11:3085-3090, 2000.

James CJ, Kobayashi K, Gotman J. Using weighted linear spatial decomposition to investigate brain activity through a set of fixed current dipoles. Clin Neurophysiol 111:773-778, 2000.

Gross DW, Merlet I, Boling W, Gotman J. Relationships between the epileptic focus and hand area in central epilepsy: Combining dipole models and anatomical landmarks. J Neurosurg 92:785-792, 2000.

Kobayashi K, James CJ, Yoshinaga H, Otsuka Y, Gotman J. The electroencephalogram through a software microscope: Non-invasive localization and visualization of epileptic seizure activity from inside the brain. Clin Neurophysiol 111:134-149, 2000.

Serles DW, Min Li L, Caramanos Z, Arnold DL, Gotman J. Relationship of interictal spike frequency to 1H-MRSI-measured NAA/Cr. Epilepsia 40:1821-1827, 1999.

Merlet I, Gotman J. Reliability of dipole models of epileptic spikes. Clin Neurophysiol 110:1013-1028, 1999.

Kobayashi K, James CJ, Nakahori T, Akiyama M, Gotman J. Isolation of epileptiform discharges from unaveraged EEG by independent component analysis. Clin Neurophysiol 110:1755-1763, 1999.

Gross DW, Gotman J. Correlation of high frequency oscillations with the sleep-wake cycle and cognitive activity in humans. Neuroscience 94:1005-1018, 1999.

Gross DW, Gotman J, Quesney LF, Dubeau F, Olivier A. Intracranial EEG with very low frequency activity fails to demonstrate an advantage over conventional recordings. Epilepsia 40:891-898, 1999.

Gotman J. Automatic detection of seizures and spikes. J Clin Neurophysiol 16:130-140, 1999.

Bernasconi A, Cendes F, Lee J, Reutens D, Gotman J. EEG background delta activity in temporal lobe epilepsy-Correlation with volumetric and spectroscopic imaging. Epilepsia 40:1580-1586, 1999.

Agarwal R, Gotman J. Adaptive segmentation of EEG using a nonlinear energy operator. IEEE Trans Biomed Eng 4:199-202, 1999.

Wu L, Gotman J. Segmentation and classification of EEG during epileptic seizures. Electroenceph Clin Neurophysiol 106:344-356, 1998.

Si Y, Gotman J, Pasupathy A, Flanagan D, Rosenblatt B, Gottesman RD. An expert system for EEG monitoring in the pediatric intensive care unit. Electroenceph Clin Neurophysiol 106:488-500, 1998.

McMackin D, Jones-Gotman M, Dubeau F, Gotman J, Lukban A, Dean G, Evans A, Lisbona R. Assymetry in regional cerebral blood flow in relation to language dominance: a study using co-registered SPECT and MRI during the intracarotid sodium amobarbital procedure. Neurology 50:943-950, 1998.

Agarwal R, Gotman J, Flanagan D, Rosenblatt B. Automatic EEG analysis during long-term monitoring in the ICU. Electroenceph Clin Neurophysiol 107:44-58, 1998.

Spanedda F, Cendes F, Gotman J. Relations between EEG seizure morphology, interhemispheric spread and mesial temporal atrophy in bitemporal epilepsy. Epilepsia 38:1300-1314, 1997.

Qu H, Gotman J. A patient-specific algorithm for the detection of seizure onset in long-term EEG monitoring: possible use as a warning device. IEEE Trans Biomed Eng 44:115-122, 1997.

Paus T, Zatorre RJ, Hofle N, Caramanos Z, Gotman J, Petrides M, Evans A. Time-related changes in neural systems underlying attention and arousal during the performance of an auditory vigilance task. J Cog Neurosci 3:392-408, 1997.

McMackin D, Dubeau F, Jones-Gotman M, Gotman J, Lukban A, Dean G, Evans A, Tampieri D, Lisbona R. Assessment of the functional effect of the intracarotid sodium amobarbital procedure using co-registered MRI/HMPAO-SPECT and SEEG. Brain Cogn 33:50-70, 1997.

Maloney KJ, Cape EG, Gotman J, Jones, BJ. High frequency, gamma electroencephalogram activity in association with sleep-wake states and spontaneous behaviors in the rat. Neuroscience 76:541-555, 1997.

Hofle N, Paus T, Reutens D, Fiset P, Gotman J, Evans A, Jones B. Regional cerebral blood flow changes as a function of delta and spindle activity during slow wave sleep in humans. J Neurosci 17:4800-4808, 1997.

Gotman J, Flanagan D, Zhang J, Rosenblatt B. Automatic seizure detection in the newborn: Methods and initial evaluation. Electroenceph Clin Neurophysiol 103:356-362, 1997.

Gotman J, Flanagan D, Rosenblatt B, Bye A, Mizrahi, EM. Evaluation of an automatic seizure detection method for the newborn EEG. Electroenceph Clin Neurophysiol 103:363-369, 1997.

Gotman J, Levtova V. Amygdala-hippocampus relationships in temporal lobe seizures: a phase-coherence study. Epilepsy Res 25:51-57, 1996.

Cendes F, Dubeau F, Andermann F, Quesney LF, Gambardella A, Jones-Gotman M, Bizzi J, Olivier A, Gotman J, Arnold DL. Significance of mesial temporal atrophy in relation to intracranial ictal and interictal stereo EEG abnormalities. Brain 119:1317-1326, 1996.

Qu H, Gotman J. A seizure warning system for long-term epilepsy monitoring. Neurology 45:2250-2254, 1995.

Gotman J, Levtova V, Olivier A. Frequency of the electroencephalographic discharge in seizures of focal and widespread onset in intracerebral recordings. Epilepsia 36:697-703, 1995.

Gambardella A, Gotman J, Cendes F, Andermann F. Focal intermittent delta activity in patients with mesial temporal atrophy: a reliable marker of the epileptogenic focus. Epilepsia 36:122-129, 1995.

Gambardella A, Gotman J, Cendes F, Andermann F. The relationship of spike foci and of clinical seizure characteristics to different patterns of mesial temporal atrophy. Arch Neurol 52:287-293, 1995.

Oguni H, Andermann F, Gotman J, Olivier A. Effect of anterior callosotomy on bilaterally synchronous spike and wave and other EEG discharges. Epilepsia 35:505-513, 1994.

Mascott C, Gotman J, Beaudet A. Automated EEG monitoring in defining a chronic epilepsy model. Epilepsia 35:895-902, 1994.

Jones-Gotman M, Bouwer MS, Gotman J. EEG slow waves and memory performance during the intracarotid amobarbital test. Epilepsia 35:61-69, 1994.

Gotman J. Computer-assisted epilepsy monitoring. Bolletino della Lega Italiana contro l'Epilessia 86/87:391-394, 1994.

Qu H, Gotman J. Improvement in seizure detection performance by automatic adaptation to the EEG of each patient. Electroenceph Clin Neurophysiol 86:79-87, 1993.

Gotman J, Levtova V, Farine B. Graphic representation of the EEG during epileptic seizures. Electroenceph Clin Neurophysiol 87:206-214, 1993.

Bouwer MS, Jones-Gotman M, Gotman J. Duration of sodium amytal effect: Behavioral and EEG measures. Epilepsia 34:61-68, 1993.

Gotman J, Wang LY. State-dependent spike detection: Validation. Electroenceph Clin Neurophysiol 83:12-18, 1992.

Gotman J, Bouwer MS, Jones-Gotman M. Intracranial EEG study of brain structures affected by internal carotid injection of amobarbital. Neurology 42:2136-2143, 1992.

Gigli GL, Gotman J. Effects of seizures, kindling, and carbamazepine on sleep organization in cats. Epilepsia 33:14-22, 1992.

Sammaritano M, Gigli GL, Gotman J. Interictal spiking during wakefulness and sleep and the localization of foci in temporal lobe epilepsy. Neurology 41:290-297, 1991.

Gotman J. Relationships between interictal spiking and seizures: Human and experimental evidence. Can J Neurol Sci 18:573-576, 1991.

Gotman J, Wang LY. State-dependent spike detection: concepts and preliminary results. Electroenceph Clin Neurophysiol 79:11-19, 1991.

Gigli GL, Gotman J. Effects of seizures and carbamazepine on interictal spiking in amygdala kindled cats. Epil Res 8:204-212, 1991.

So N, Gotman J. Changes in seizure activity following anticonvulsant drug withdrawal. Neurology 40:407-413, 1990.

So N, Gotman J. Quantitative EEG analysis of carbamazepine effects on amygdaloid kindled seizures in cats. Electroenceph Clin Neurophysiol 76:63-72, 1990.

Panet-Raymond D, Gotman J. Can slow waves in the electrocorticogram (ECoG) help localize epileptic foci? Electroenceph Clin Neurophysiol 75:464-473, 1990.

Panet-Raymond D, Gotman J. Asymmetry in delta activity in patients with focal epilepsy. Electroenceph Clin Neurophysiol 75:474-481, 1990.

Gotman J. Automatic seizure detection: Improvements and evaluation. Electroenceph Clin Neurophysiol 76:317-324, 1990.

Gotman J, Koffler DJ. Interictal spiking increases after seizures but does not after decrease in medication. Electroenceph Clin Neurophysiol 72:7-15, 1989.

Sherwin A, Robitaille Y, Quesney LF, Olivier A, Villemure JG, Leblanc R, Feindel W, Andermann E, Gotman J, Andermann F, Ethier R, Kish S. Excitatory amino acids are evaluated in human epileptic cerebral cortex. Neurology 38:920-923, 1988.

Gigli GL, Gotman J, Thomas ST. Sleep alterations after acute administration of carbamazepine in cats. Epilepsia 29:748-752, 1988.

Milton JG, Gotman J, Remillard GM, Andermann F. Timing of seizure recurrence in adult epileptic patients: A statistical analysis. Epilepsia 28:471-478, 1987.

Gotman J. Interhemispheric interactions in seizures of focal onset: data from human intracranial recordings. Electroenceph Clin Neurophysiol 67:120-133, 1987.

Schaul N, Green L, Peyster R, Gotman J. Structural determinants of electro-encephalographic findings in acute hemispheric lesions. Ann Neurol 20:703-711, 1986.

Marciani MG, Gotman J. Effects of drug withdrawal on location of seizure onset. Epilepsia 27:423-431, 1986.

Marciani MG, Gotman J, Andermann F, Olivier A. Patterns of seizure activation following withdrawal of anti- epileptic medication. Neurology 35:1537-1543, 1985.

Koffler DJ, Gotman J. Automatic detection of spike-and-wave bursts in ambulatory EEG recordings. Electroenceph Clin Neurophysiol 61:165-180, 1985.

Gotman J. Practical use of computer-assisted EEG interpretation in epilepsy. J Clin Neurophysiol 2:251-265, 1985.

Gotman J, Marciani, MG. Electroencephalographic spiking activity, drug levels and seizure occurrence in epileptic patients. Ann Neurol 17:597-603, 1985.

Kostopoulos G, Gotman J. Computer assisted analysis of relations between single-unit activity and spontaneous EEG. Electroenceph Clin Neurophysiol 57:69-82, 1984.

Gotman J. Relationships between triggered seizures, spontaneous seizures and interictal spiking in the kindling model of epilepsy. Exp Neurol 84:259-273, 1984.

Gotman J, Marciani MG, Gloor P, Quesney LF, Sherwin A. Effects of withdrawal of anticonvulsant medication on ictal and interictal EEG activity. Clin Neuropharmacol 7:132-133, 1984.

Gotman J. Measurement of small time differences between EEG channels: method and application to epileptic seizure propagation. Electroenceph Clin Neurophysiol 56:501-514, 1983.

Avoli M, Gloor P, Kostopoulos G, Gotman J. An analysis of penicillin-induced generalized spike-and-wave discharges using simultaneous recordings of cortical and thalamic neurons. J Neurophysiol 50:819-837, 1983.

Gotman J. Automatic recognition of epileptic seizures in the EEG. Electroenceph Clin Neurophysiol 54:530-540, 1982.

Gotman J, Ives JR, Gloor P, Olivier A, Quesney LF. Changes in interictal EEG spiking and seizure occurrence in humans. Epilepsia 23:432-433, 1982.

Gotman J, Gloor P, Quesney LF, Olivier A. Correlation between EEG changes induced by diazepam and the localization of epileptic spikes and seizures. Electroenceph Clin Neurophysiol 54:614-621, 1982.

Schaul N, Gloor P, Gotman J. The EEG in deep midline lesions. Neurology 31:157-167, 1981.

Kostopoulos G, Gloor P, Pellegrini A, Gotman J. A study of the transition from spindles to spike and wave discharge in feline generalized penicillin epilepsy: Microphysiological features. Exp Neurol 73:55-77, 1981.

Gotman J. A computer system to assist in the evaluation of the EEG of epileptic patients. Res Meth Instr 13:525-531, 1981.

Gotman J. Interhemispheric relations during bilateral spike-and-wave activity. Epilepsia 22:453-466, 1981.

Gotman J, Ives JR, Gloor P. Frequency content of EEG and EMG at seizure onset: possibility of removal of EMG artefact by digital filtering. Electroenceph Clin Neurophysiol 52:626-639, 1981.

Gotman J. Quantitative measurements of epileptic spike morphology in the human EEG. Electroenceph Clin Neurophysiol 48:551-557, 1980.

Gotman J, Ives JR, Gloor P. Automatic recognition of interictal epileptic activity in prolonged EEG recordings. Electroenceph Clin Neurophysiol 46:510-520, 1979.

Schaul N, Ball GJ, Gloor P, Gotman J. The electromicrohphysiology of delta waves induced by systemic atropine. Brain Res 143:475-486, 1978.

Gotman J, Gloor P, Schaul N. Comparison of traditional reading of the EEG and automatic recognition of interictal epileptic activity. Electroenceph Clin Neurophysiol 44:48-60, 1978.

Gotman J, Gloor P. Automatic recognition and quantification of interictal epileptic activity in the human scalp EEG. Electroenceph Clin Neurophysiol 41:513-529, 1976.

Gotman J, Gloor P, Ray WF. A quantitative comparison of traditional reading of the EEG and interpretation of computer-extracted features in patients with supratentorial brain lesions. Electroenceph Clin Neurophysiol 38:623-639, 1975.

Gotman J, Skuce DR, Thompson CJ, Gloor P, Ives JR, Ray WF. Clinical applications of spectral analysis and extraction of features from electroencephalograms with slow waves in adult patients. Electroenceph Clin Neurophysiol 35:225-235, 1973.


Book Chapters


LeVan P, Gotman J. Automatic detection of epileptic spikes. In: Textbook of Epilepsy Surgery, edited by H.O. Lüders, W. Bongaman, I.M. Najm, Taylor & Francis, Abingdon, UK, 2008, in press.


LeVan P, Gotman J. Computer-assisted data collection and analysis. In: Epilepsy: A Comprehensive Textbook, 2nd edition, edited by J. Engel Jr., T.A. Pedley,  J. Aicardi, Lippincott Williams & Wilkins, Philadelphia, 2007, in press.


Velis D, Plouin P, Gotman J, Lopes da Silva F, and the members of the ILAE DMC Subcommitee on Neurophysiology. ILAE Commission Report - Recommendations Regarding the Requirements and Applications for Long-term Recordings in Epilepsy. Epilepsia: 48:379-384, 2007.

Gotman J. Noninvasive methods for evaluating the localization and propagation of epileptic activity. In: Crosslinks in Neurophysiology and Epilepsy: A symposium in honour of Fernando H. Lopes da Silva, edited by D.N. Velis, W. van Emde Boas, R.A. Voskuyl, W.J. Wadman, Blackwell Publishing. Epilepsia 44 (Suppl.12) 21-29, 2003

Gotman J. Automatic detection of epileptic seizures. In: Handbook of Clinical Neurophysiology, Volume: Presurgical assessment of the epilepsies with clinical neurophysiology and functional imaging, edited by F. Rosenow, H. Luders, Elsevier Science, 2003, in press.

Gotman J, Agarwal R. Automatic sleepstaging and event detection in the study of relationships between sleep and epilepsy. In: Sleep and Epilepsy: The clinical spectrum, Chapter 26, edited by C. W. Bazil, B.A. Malow, M.R. Sammaritano, Elsevier Science B.V., 2002, p. 313-321.

Gotman J. Computer-assisted data collection and analysis. In: The treatment of epilepsy: Principles and Practice, edited by E. Wyllie, Lippincott, Williams & Wilkins, 2001, p. 209-224.

Gotman J. Can seizure analysis tell us where the focus is? In: Advances in Neurology, Neocortical epilepsies, Volume 84, edited by P.D. Williamson, A.M. Siegel, D.W, Roberts, V.M. Thadani, and M.S. Gazzaniga, Philadelphia: Lippincott Williams & Wilkins, 2000, p. 299-315.

Rosenblatt B, Gotman J. Computerized EEG monitoring. In: Seminars in pediatric neurology, New technologies in pediatric neurology, edited by J. B. Bodensteiner, Philadelphia, PA: W.B. Saunders Company, 1999, p. 120-127.

Gotman J. Monitorizacao de Longa Duracao no Final do Seculo: O Presente e o Futuro. In: Fundamentos Neurobiologicos das Epilepsias, edited by J. Costa da Costa, A. Palmini, Yacubian E.M.T., and E. A. Cavalheiro, Sao Paulo:Lemos-Editorial & Graficos Ltda., 1998, p. 913-938.

Gotman J, Ives JR. Computer-assisted data collection and analysis. In: Epilepsy: A comprehensive Textbook., edited by J. Engel Jr. and T. A. Pedley, Philadelphia: Lippincott-Raven, 1997, p. 1029-1044.

Gotman J, Ives JR. Computer-assisted data collection and analysis. In: The Treatment of Epilepsy: Principles and Practice, edited by E. Wyllie, Baltimore: Williams & Wilkins, 1997, p. 280-291.

Sharbrough FW, Gotman J. Overview of new diagnostic techniques. In: Surgical Treatment of the Epilepsies, edited by J. Engel Jr., New York: Raven Press, 1993, p. 155-160.

Jones-Gotman M, Barr WB, Dodrill CB, Gotman J, Meador KJ, Rausch R, Sass KJ, Sharbrough FW, Silfvenius H, Wieser HG. Postscript: Controversies Concerning the Use of Intraarterial Amobarbital Procedures. In: Surgical Treatment of the Epilepsies, edited by J. Engel Jr., New York: Raven Press, 1993, p. 445-450.

Gotman J, Burgess RC, Darcey TM, Harner RN, Ives JR, Lesser RP, Pijn JPM, Velis D. Computer applications. In: Surgical Treatment of the Epilepsies, edited by J. Engel Jr., New York: Raven Press, 1993, p. 429-444.

Gotman J. Computer-assisted EEG analysis. In: The Treatment of Epilepsy. Principles and Practice, edited by E. Wyllie, Philadelphia: Lea & Febiger, 1993, p. 268-277.

Jacobs EC, Burgess RC, Collura TF, Gotman J, Lagerlund TD, Lesser RP, Webber WRS. EEG digitalization: Format for storage and interlab transmission. In: Epilepsy Surgery, edited by H. O. Lüders, New York: Raven Press, 1991, p. 759-761.

Gotman J. Seizure spread. In: Epilepsy Surgery, edited by H. O. Lüders, New York:Raven Press, 1991, p. 349-354.

Gotman J. Automatic detection of seizures and spikes in the EEG. In: Epilepsy Surgery, edited by H. O. Lüders, New York:Raven Press, 1991, p. 307-316.

Gotman J. Automated detection and analysis of seizures and spikes in the EEG. In: Recent Advances In Epilepsy, No. 5, edited by T. A. Pedley and B. S. Meldrum, Edinburgh:Churchill Livingston, 1991, p. 73-90.

Gotman J. The use of computers in analysis and display of EEG and evoked potentials. In: Current Practice Of Clinical Electroencephalography, Vol. 2, edited by D. D. Daly and T. A. Pedley, New York:Raven Press, 1990, p. 51-83.

Gotman J. Automated analysis of ambulatory EEG recordings. In: Ambulatory EEG Monitoring, edited by J. S. Ebersole, New York:Raven Press, 1989, p. 97-110.

Andermann F, Olivier A, Gotman J, Sergent J. Callosotomy for the treatment of patients with intractable epilepsy and the Lennox-Gastaut Syndrome. In: Neurology and Neurobiology. The Lennox-Gastaut Syndrome, Vol. 45,Anonymous 1988, p. 361-376.

Gotman J. Biorhythmic modulation of seizure events in focal epilepsy. In: Advances In Epileptology, Vol. 16, edited by P. Wolf, M. Dam, D. Janz, and F. Dreifuss, New York:Raven Press, 1987, p. 699-703.

Gotman J, Darcey TM, Lieb JP. Commentary: Computer analysis of seizure recordings. In: Surgical Treatment of the Epilepsies, edited by J. Engel Jr., New York:Raven Press, 1987, p. 361-369.

Gotman J. Computer analysis of EEG in epilepsy. In: Handbook of Electroencephalography and Clinical Neurophysiology, Vol. 2, edited by F. H. Lopes da Silva, W. Storm van Leeuwen, and A. Rémond, New York:Elsevier, 1986, p. 171-204.

Gotman J. Computer analysis during intensive monitoring of epileptic patients. In: Intensive Neurodiagnostic Monitoring. Advances in Neurology, Vol. 46, edited by R. J. Gumnit, New York:Raven Press, 1986, p. 249-269.

Gotman J. Automatic recognition of interictal spikes. In: Long-Term Monitoring In Epilepsy, edited by J. Gotman, J.R. Ives, and P. Gloor, Amsterdam:Elsevier, 1985, p. 93-114.

Gotman J. Seizure recognition and analysis. In: Long-Term Monitoring In Epilepsy, edited by J. Gotman, J. R. Ives, and P. Gloor, Amsterdam:Elsevier, 1985, p. 133-145.

Gotman J, Ives JR, Gloor P, Quesney LF, Bergsma P. Long-term monitoring at the Montreal Neurological Institute. In: Long-Term Monitoring In Epilepsy, edited by J. Gotman, J. R. Ives, and P. Gloor, Amsterdam:Elsevier, 1985, p. 327-340.

Gotman J, Ives JR, Gloor P. A computer system for prolonged EEG recordings if ictal and interictal activity in epilepsy. In: Advances In Epileptology: XIIIth Epilepsy International Symposium, edited by H. Kazamatsuri, M. Seino, and A. Ward, New York:Raven Press, 1982, p. 167-172.

Feindel W, Gloor P, Yamamoto YY, Gotman J, Shimizu H, Ochs R. Correlation of EEG and topographic cerebral blood flow in epilepsy by Positron Emission Tomography. In: Advances in Epileptology, XIII Epilepsy International Symposium, edited by H. Akimoto, H. Kazamatsuri, M. Seino, and A. Ward, New York:Raven Press, 1982, p. 151-156.

Gotman J. Problems of presentation of analytic results. In: Contemporary Clinical Neurophysiology, Elsevier, Amsterdam, 1978, p. 191-197.




Gotman J. Pierre Gloor, 1923-2003. Clin Neurophysiol 115:1235-1236, 2004.


Gotman J. L’analyse de l’EEG: de Berger à nos jours. Epileptic Disorders 3: SI 7-SI 10, 2001. (Special Issue 2001: odyssée de l’EEG, guest editor).


Grossman M, Gotman J. As time goes by - High temporal and spatial resolution in cognitively related cortical function. Neurology 57:1947-1948, 2001. 



Information about epilepsy: International League against Epilepsy